OVEREXPRESSION OF TP53INP2 PROMOTES APOPTOSIS IN CLEAR CELL RENAL CELL CANCER VIA CASPASE-8/TRAF6 SIGNALING PATHWAY

Overexpression of TP53INP2 Promotes Apoptosis in Clear Cell Renal Cell Cancer via Caspase-8/TRAF6 Signaling Pathway

Clear cell renal cell cancer (ccRCC) is a tumor of high malignancy, which can escape apoptosis.The tumor protein p53-inducible nuclear protein 2 (TP53INP2), known as an autophagy protein, is the essential part for autophagosome formation and sensitizes cells to apoptosis.Our study is aimed at exploring the role of TP53INP2 in ccRCC.We have identifi

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Power Generation Expansion Optimization Model Considering Multi-Scenario Electricity Demand Constraints: A Case Study of Zhejiang Province, China

Reasonable and effective power planning contributes a lot to energy efficiency improvement, as well as the formulation of future economic and energy policies for a region.Since only a few provinces in China have nuclear power plants so far, nuclear power plants were not considered in many provincial-level power planning models.As an extremely impor

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Saint Plato, the Martyr of Ankara

Beliefs and religious practices related to martyrdom and sainthood have existed since the first periods of Christianity, and the nature of these practices was formed by the conditions of the Early Christian period in which believers omen 25l gaming desktop gt15-0340qd were persecuted and subject to hardship and torture.During this time, the practic

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Optimization of Ultrasound-Assisted Extraction of Flavonoids from Olive (Olea europaea) Leaves, and Evaluation of Their Antioxidant and Anticancer Activities

Olea europaea leaves are the major byproduct of olive farming.In this study, ultrasound-assisted extraction of flavonoids from olive leaves was optimized using response surface methodology, and the flavonoid compounds and their antioxidant and anticancer activities were investigated by high performance liquid chromatography.The results showed that

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